Anti-Struvite
Efficacy
Dissolution of existing struvite crystals and stones in the urinary bladder and prevention of the formation of struvite is only possible by a low urinary pH and low concentrations of the struvite components. Struvite consists of magnesium, ammomium and phosphate and either dissolves or does not form at a urinary pH lower than 6.5. Sanimed Anti-struvite contains an appropriate amount of urine acidifier so that the average urinary pH will be 6.2. This pH has anti-struvite activity and does not entail the risk of acidosis. The low levels of magnesium, phosphate and protein further stimulate dissolution of struvite and inhibit its formation. Thus, Sanimed Anti-struvite can be used in patients with non-obstructive struvite urolithiasis as well as in patients sensitive to recurrence of struvite formation. On the basis of literature data (Osborne et al., 1990; Houston et al., 2004) and the ideal composition of Sanimed Anti-struvite, the anticipated time required for complete dissolution of struvite in the urinary bladder on average is 4 weeks.
The formulation of Sanimed Anti-Struvite reduces the risk of calcium oxalate urolithiasis. The diet is low in calcium and glycine (substrate for the synthesis of oxalate).